巻号一覧
11 巻, 12 号
選択された号の論文の20件中1～20を表示しています
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富田 真雄, 菊池 徹, 別所 清, 犬伏 康夫1963 年 11 巻 12 号 p. 1477-1483
発行日: 1963/12/25
公開日: 2008/03/31
ジャーナル フリーPotassium-liq. ammonia cleavage of O-methylisopilocereine yielded IIa and IIb as bisected bases. This suggested that the structure of isopilocereine is either Ia or XIa, although the previous assignment of Ia to pilocereine and piloceredine by Djerassi, et al. excluded structure (Ia). The synthesis of lophocerine (IIa) is also reported.抄録全体を表示PDF形式でダウンロード (751K) -
富田 真雄, 菊池 徹, 別所 清, 堀 年男, 犬伏 康夫1963 年 11 巻 12 号 p. 1484-1490
発行日: 1963/12/25
公開日: 2008/03/31
ジャーナル フリーAs an important intermediate in the synthesis of Ib, several ways of preparing the dialdehyde (IX) were investigated and a considerable increase in total yield was achieved. Synthesis of XXXI, an intermediate in the synthesis of IIb, was also examined.抄録全体を表示PDF形式でダウンロード (774K) -
別所 清1963 年 11 巻 12 号 p. 1491-1494
発行日: 1963/12/25
公開日: 2008/03/31
ジャーナル フリーBase (I), which had been presumed to be O-methylisopilocereine, was synthesized and two racemic diastereomers were isolated. However, the fact that these bases are not O-methylisopilocereine suggested that the latter should be represented by formula (XII), which had been assigned to O-methylpilocereine and O-methylpiloceredine.抄録全体を表示PDF形式でダウンロード (510K) -
別所 清1963 年 11 巻 12 号 p. 1495-1499
発行日: 1963/12/25
公開日: 2008/03/31
ジャーナル フリーBase (I), the structure of which had been considered to be that of O-methylpilocereine and O-methylpiloceredine, was synthesized from diphenyl ether dicarboxaldehyde (III). One of its racemic diastereomers was isolated in crystalline state. Both the crystalline base (I) and the mixture of its diastereomers had identical infrared spectra with O-methylisopilocereine in chloroform solution. The chromatographic behaviours also suggested that the formula (I) represents O-methylisopilocereine, not O-methylpilocereine.抄録全体を表示PDF形式でダウンロード (593K) -
別所 清1963 年 11 巻 12 号 p. 1500-1503
発行日: 1963/12/25
公開日: 2008/03/31
ジャーナル フリーBase (Ib) was synthesized by the Ullmann condensation between VII and VIII, and the two racemic diastereomers were obtained in crystalline states. One of them was proved to be O-methylisopilocereine, while the other was identified with the diastereomer obtained by another synthetic method. Non-identities of them with O-methylpilocereine, to which the formula (Ib) had been inadequately assigned, were also proved.抄録全体を表示PDF形式でダウンロード (495K) -
別所 清1963 年 11 巻 12 号 p. 1504-1507
発行日: 1963/12/25
公開日: 2008/03/31
ジャーナル フリーThe potassium-liq. ammonia cleavage of O-methylpilocereine was carried out in order to re-examine the structure (Ia) of pilocereine. In addition to the expected bases (II, IIIb, IVa, and IIIa), isopilocereine (Ia) and a phenolic base which is considered to be V were obtained. This result and new molecular formula C45H65O6N3 proposed lately by Djerassi, et al. pointed out the structure of pilccereine to be VIa. The formation of isopilocereine on treatment of pilocereine with potassium-liq. ammonia was illustrated as a normal cleavage reaction.抄録全体を表示PDF形式でダウンロード (506K) -
別所 清1963 年 11 巻 12 号 p. 1507-1510
発行日: 1963/12/25
公開日: 2008/03/31
ジャーナル フリーThe structure of isopilocereine (Ib) and desmethylisopilocereine (Ic) were established by potassium-liq. ammonia cleavage reactions of their O-ethyl ethers, Id and Ie.抄録全体を表示PDF形式でダウンロード (487K) -
尾形 秀1963 年 11 巻 12 号 p. 1511-1516
発行日: 1963/12/25
公開日: 2008/03/31
ジャーナル フリーReaction of excess acetyl chloride on a 3-substituted 4-nitro-6-methylpyridazine 1-oxide (Ia, b, c and XIII) result in the formation of 3-substituted 4-chloro-6-formylpyridazine 1-oxide oximes (IIa, b, c and XVIII), together with 3-substituted 4-chloro-6-methylpyridazine 1-oxides (IIa, b, c and XVII). Reaction of 3-methyl-4-nitropyridazine 1-oxide (XII) and 4-nitro-5-methylpyridazine 1-oxide (XIV) with acetyl chloride gave only 3-methyl-4-chloropyridazine 1-oxide (XIII) and 4-chloro-5-methylpyridazine 1-oxide (XV) respectively.抄録全体を表示PDF形式でダウンロード (685K) -
尾形 秀1963 年 11 巻 12 号 p. 1517-1522
発行日: 1963/12/25
公開日: 2008/03/31
ジャーナル フリーThe reaction of methylpyridazine N-oxides with amyl nitrite in the presence of sodium amide in liquid ammonia afforded the corresponding syn-aldoximes. These syn-aldoximes were isomerized to anti-aldoximes with hydrochloric acid or heating alone except the case of some aldoximes. The configuration of the aldoximes was confirmed by the infrared and nuclear magnetic resonance spectra.抄録全体を表示PDF形式でダウンロード (645K) -
尾形 秀1963 年 11 巻 12 号 p. 1522-1527
発行日: 1963/12/25
公開日: 2008/03/31
ジャーナル フリー3-Chloro, 3-methyl, 3-methoxy, 3-benzyloxy, and 3-phenyl-6-cyanopyridazine (III, VI, X, XII, XIV) was synthesized from 3-chloro, 3-methyl, 3-methoxy, 3-benzyloxy, and 3-phenylpyridazine 1-oxide (II, V, IX, XI, XIII).抄録全体を表示PDF形式でダウンロード (692K) -
尾形 秀, 加納 日出夫, 通 和夫1963 年 11 巻 12 号 p. 1527-1539
発行日: 1963/12/25
公開日: 2008/03/31
ジャーナル フリーCinnoline 1-oxide (II), cinnoline 2-oxide (III), 4-methylcinnoline 1-oxide (V), 4-methylcinnoline 2-oxide (VI), 3-chlorocinnoline 1-oxide (VIII), and 3-methoxycinnoline 1-oxide (XXI) were synthesized. For confirmation of the structure of these compounds, cinnoline 1-oxide (II) and 3-chlorocinnoline 1-oxide (VIII) were prepared from their corresponding 5, 6, 7, 8-tetrahydro derivatives (XI and XIII) by bromination with N-bromosuccimide followed by dehydrobromination with sodium methoxide. The structures of isomeric 4-methylcinnoline N-oxides were determined by the application of ultraviolet and nuclear magnetic resonance spectroscopies. The nuclear magnetic resonance spectra of the cinnoline N-oxides synthesized were examined. The interpretation of the spectra was made in connection with those of pyridazine N-oxides and of quinoline N-oxides. The proton H8 shows its signal peak at a lower field than do the other protons, owing to the magnetic anisotropy effect of the N-O group.抄録全体を表示PDF形式でダウンロード (1230K) -
黒岩 幸雄, 嶺岸 謙一郎, 奥井 誠一1963 年 11 巻 12 号 p. 1540-1545
発行日: 1963/12/25
公開日: 2008/03/31
ジャーナル フリーThe demethylation activity for the N-methylbarbiturates was localized in the microsomal fraction and required NADPH and oxygen. This activity was increased markedly with pretreatment of some barbiturates but not with carcinogenic substances such as DAB, 3-MC and benzpyrene. The activity of the demethylation or hydroxylation of barbiturates was generally decreased by the pretreatment of carcinogenic substances. In accord with the increase of enzyme activity, in the time course of induction after the pretreatment of phenobarbital, two maximum peaks were appeared around 24∼40 hours and 60∼70 hours when cyclobarbital, methylbarbital, and 3-methyl-MAB were employed as the substrates. By the pretreatment of 3-MC the demethylation of 3-methyl-MAB was stimulated, but the demethylation of methylbarbital was not.抄録全体を表示PDF形式でダウンロード (645K) -
川崎 敏男, 宮原 一元1963 年 11 巻 12 号 p. 1546-1550
発行日: 1963/12/25
公開日: 2008/03/31
ジャーナル フリーThin layer chromatography on silica gel-gypsum was applied to steroid saponins and their derivatives such as peracetates and permethylates. The method has many advantages over paper chromatography in speed, sensitivity, and, above all, in resolving power of the closely related high molecular weight saponins and of the slightly polar derivatives.抄録全体を表示PDF形式でダウンロード (582K) -
渡辺 寿美子, 上田 武雄1963 年 11 巻 12 号 p. 1551-1556
発行日: 1963/12/25
公開日: 2008/03/31
ジャーナル フリーTwelve compounds of phenylpyruvic acid thiosemicarbazone derivatives substituted with alkyl group, hydroxy group, alkoxy group or halogen atom at 2, 3-and/or 4-position in benzene ring, nine compounds of 3-thioxo-6-aryl-3, 4-dihydro-as-triazin-5 (2H)-one, five compounds of 3-methylthio-6-aryl-as-triazin-5 (4H)-one, and five compounds of 6-aryl-as-triazine-3, 5 (2H, 4H)-dione were newly synthesized. Among these compounds, 3, 4-dimethoxyphenylpyruvic acid thiosemicarbazone showed remarkable activity on the multiplication of the Mahoney strain of polio virus type 1, while 6-phenyl-, and 6-(p-propoxybenzyl)-3, 4-dihydro-as-triazin-5 (2H)-one, and 6-(p-chlorobenzyl)-as-triazine-3, 5(2H, 4H)-dione were slightly effective on the virus by using 100×TCID50 of the virus.抄録全体を表示PDF形式でダウンロード (590K) -
岩井 一成, 平岡 哲夫1963 年 11 巻 12 号 p. 1556-1563
発行日: 1963/12/25
公開日: 2008/03/31
ジャーナル フリーThe Stevens type rearrangement of phenylpropargylammonium halide derivatives was carried out. This rearrangement usually consists of 1, 2-shift of migratory group, however, it was found that bis phenylpropargylammonium halide derivative underwent the 1, 4-shift to give an allenic compound. The rearrangement was extended to a ring expansion reaction.抄録全体を表示PDF形式でダウンロード (890K) -
岩井 一成, 平岡 哲夫1963 年 11 巻 12 号 p. 1564-1568
発行日: 1963/12/25
公開日: 2008/03/31
ジャーナル フリーThe intramolecular cyclization reaction of propargylammonium halide derivatives was carried out and it was found that dimethyl (2-propynyl) (3-phenyl-2-propynyl)-ammonium bromide (II) gave 2-methylbenz [f] isoindoline (III) on treatment with sodium ethoxide in alcohol and 2-methyl-1-(2-propynyl) pyridinium bromide gave 2-methyl-indolizine (XII) on heating in sodium bicarbonate solution. Analogously, 2-amino-1-(2-propynyl) pyridinium bromide (XV) afforded 2-methylimidazo [1, 2-α] pyridine (XVI).抄録全体を表示PDF形式でダウンロード (581K) -
岩重 忠博, 浅井 素次, 岩井 一成1963 年 11 巻 12 号 p. 1569-1575
発行日: 1963/12/25
公開日: 2008/03/31
ジャーナル フリーEthyl 5-O-(2'-tetrahydropyranyl)-2, 3-anhydro-β-DL-lyxofuranoside (VIDL) was predominantly formed by the action of alkali on a chlorohydrin derivative, which was prepared by hypochlorous acid addition of 2'-ethoxy-5-(2'-tetrahydropyranyloxy) methyl-2, 5-dihydrofuran (I). Then, ethyl 3-amino-3-deoxy-β-DL-arabinofuranoside (IXDL) was synthesized from VIDL.抄録全体を表示PDF形式でダウンロード (720K) -
柴田 承二, 荻原 幸夫1963 年 11 巻 12 号 p. 1576-1578
発行日: 1963/12/25
公開日: 2008/03/31
ジャーナル フリーThe structures of ustilaginoidin B, C28H18O11, m.p. >300°, [α]25D-360°(dioxan) and ustilaginoidin C, C28H18O12, m.p. >300°, [α]25D-260°(dioxan) which were isolated as the pigments of Ustilaginoidea virens (COOKE) TAKAHASHI, were studied mostly by the NMR spectral analyses of their peracetates to conclude as being formulated as II (R=H) and III (R=H), respectively.抄録全体を表示PDF形式でダウンロード (366K) -
佐藤 良博, 田中 篤治, 加藤 彌次, 津田 恭介1963 年 11 巻 12 号 p. 1579-1585
発行日: 1963/12/25
公開日: 2008/03/31
ジャーナル フリーInkubation von Progesteron (I) mit Kulturen von Syncephalastrum racemosum COHN ergab neben den bekannten Produkten, namlich 15β-Hydroxyprogesteron (II), 6β, 11α-Dihydroxyprogesteron (VI), 7β, 15β-Dihydroxyprogesteron (IV) und 7β, 14α, 15β-Trihydroxyprogesteron (VII), noch unbekannte Produkte, namlich 6β, 15β-Dihydroxyprogesteron (V) und 15β-Hydroxy-5α-pregnan-3, 6-20-trion (III).抄録全体を表示PDF形式でダウンロード (888K) -
太田 明広1963 年 11 巻 12 号 p. 1586-1587
発行日: 1963/12/25
公開日: 2008/03/31
ジャーナル フリーBei der Einwirkung von Bleitetrabenzoat auf Chinolin-N-oxyd (I) und bei der Oxydation von 2-Benzoyloxychinolin (IV) mit Permaleinsaure wurde N-Benzoyloxycarbostyril (II) erhalten. Dabei wurde der Mechanismus der Bleitetraacetat-Oxydation von Chinolin-N-oxyd (I) vorgeschlagen.抄録全体を表示PDF形式でダウンロード (360K)
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