An Efficient Synthesis of 4-Heterofunction-Substituted 3-(1-Hydroxy)ethylazetidin-2-ones from 3-(1-Hydroxy)ethyl-4-phenylsulfinylazatidin-2-one by Reaction with Silylated Heteronucleophiles

Yasuyuki KITA; Norio SHIBATA; Naoki YOSHIDA; Takashi TOHJO

doi:10.1248/cpb.40.1733

北泰行, 柴田哲男, 吉田直樹, 東條隆

著者情報

キーワード: 4-sulfinylazetidin-2-one, silylated heteronucleophile, 3-(1-hydroxy)ethylazetidin-2-one, substitution

ジャーナルフリー

1992 年 40 巻 7 号 p. 1733-1736

DOI https://doi.org/10.1248/cpb.40.1733

詳細

抄録

3-(1-tert-Butyldimethylsiloxy)ethyl-4-sulfinylazetidin-2-one was reacted with silylated N-, S-, O-, and P-nucleophiles in the presence of a catalytic amount of ZnI₂ to give the corresponding trans-4-heterofunction-substituted azetidin-2-ones in high yelids.

責任著者(Corresponding author)

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