Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Notes
Chemical Structures and Hepatoprotective Effects of Constituents from Cassia auriculata Leaves
Seikou Nakamura, Fengming Xu, Kiyofumi Ninomiya, Souichi Nakashima, Yoshimi Oda, Toshio Morikawa, Osamu Muraoka, Masayuki Yoshikawa, Hisashi Matsuda
著者情報
キーワード: Cassia auriculata, avaraoside I, avaraol I, Ayurvedic traditional medicine, hepatoprotective effect
ジャーナル フリー HTML

2014 年 62 巻 10 号 p. 1026-1031

詳細
本文（HTML形式） PDFをダウンロード (622K)
メタデータをダウンロード RIS形式

(EndNote、Reference Manager、ProCite、RefWorksとの互換性あり)

BIB TEX形式

(BibDesk、LaTeXとの互換性あり)

テキスト
メタデータのダウンロード方法
発行機関連絡先
抄録
An 80% aqueous acetone extract of Cassia auriculata leaves was found to show a protective effect on D-galactosamine-induced cytotoxicity in primary cultured mouse hepatocytes. From the 80% aqueous acetone extract, we isolated a new benzocoumarin glycoside, avaraoside I (1), and a new flavanol dimer, avaraol I (2), together with 29 known constituents. The structures of the new compounds were elucidated on the basis of chemical and physicochemical evidence. In addition, three isolated compounds, pseudosemiglabrin (15, 0.0011%), (2S)-7,4′-dihydroxyflavan(4β→8)-catechin (22, 0.00075%), and (2S)-7,4′-dihydroxyflavan(4β→8)-gallocatechin (23, 0.092%), displayed hepatoprotective effects equivalent to that of the hepatoprotective agent, silybin.
著者関連情報
© 2014 The Pharmaceutical Society of Japan
前の記事 次の記事
お気に入り & アラート

閲覧履歴
このページを共有する
feedback
 Top
OSZAR »