Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Notes
Sesquiterpenoids and Lignans from the Roots of Syringa pinnatifolia
Ze-Ming Zhang, Chun-Hua Wang, Xiao-Jie Zeng, Qiu Qiu, Wei Tang, Guo-Qiang Li, Yao-Lan Li, Guo-Cai Wang
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キーワード: Syringa pinnatifolia, Oleaceae, sesquiterpenoid, lignan, anti-oxidant activity, 2,2-diphenyl-1-picrylhydrazyl (DPPH)
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2014 年 62 巻 10 号 p. 1009-1012

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Two new sesquiterpenoids, pinnatifone A (1) and pinnatifone B (2), and two new lignans, pinnatifolin (3) and isopinnatifolin (4), along with six known lignans (5–10), were isolated from the roots of Syringa pinnatifolia. The structures of the new compounds were elucidated by extensive spectroscopic methods, including NMR, MS, UV, and IR spectra. The lignans were screened for their anti-oxidant activity (2,2-diphenyl-1-picrylhydrazyl (DPPH) assay). Most of them showed potent anti-oxidant activity, especially compound 5, whose potent anti-oxidant activity had an SC50 value higher than that of the positive control vitamin C.
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© 2014 The Pharmaceutical Society of Japan
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