Okajimas Folia Anatomica Japonica
Online ISSN : 1881-1736
Print ISSN : 0030-154X
ISSN-L : 0030-154X
Effects of Monocular Enucleation on Calbindin-D 28k and c-Fos Expression in the Lateral Geniculate Nucleus in Rats
Daniel GONZALEZ, Irawan SATRIOTOMO, Takanori MIKI, Kyoung-Youl LEE, Toshifumi YOKOYAMA, Tetsuo TOUGE, Yoshiki MATSUMOTO, Hong-Peng LI, Shigeki KURIYAMA, Yoshiki TAKEUCHI
著者情報
キーワード: Enucleation, Lateral geniculate nucleus, Calbindin-D 28k, c-Fos, Neuronal degeneration
ジャーナル フリー

2005 年 82 巻 1 号 p. 9-18

詳細
PDFをダウンロード (444K)
メタデータをダウンロード RIS形式

(EndNote、Reference Manager、ProCite、RefWorksとの互換性あり)

BIB TEX形式

(BibDesk、LaTeXとの互換性あり)

テキスト
メタデータのダウンロード方法
発行機関連絡先
抄録
The present study was undertaken to evaluate the effects of monocular enucleation on the calbindin-D 28k (CB) and c-Fos immunoreactive (IR) neurons in the lateral geniculate nucleus (LGN) complex of adult rats. The enucleation resulted in neuronal degeneration and decrease of neurons in the LGN complex. Our study demonstrated a decrease of CB-IR neuronal density on the contralateral side of the ventral (vLGN) and dorsal LGN (dLGN) until 12 weeks post-enucleation (PE). On the ipsilateral side, CB-IR neuronal density in the dLGN and vLGN showed significant and continuous decrease until 48 and 12 weeks PE, respectively. In an additional experiment, c-Fos-IR neurons were increased at 2 days PE in the vLGN with ipsilateral predominance. At 7 days, c-Fos-IR neurons on the ipsilateral vLGN were still higher than those of pre-enucleated rats. The present results suggest that monocular enucleation affects the expression of the CB and c-Fos in the LGN complex. It is indicated that these may play an important role in the neuronal degeneration and neuroplasticity of the subvisual system in rats.
著者関連情報
© 2005 Editorial Board of Okajimas Folia Anatomica Japonica
前の記事 次の記事
お気に入り & アラート

閲覧履歴
前身誌

Folia Anatomica Japonica

このページを共有する
feedback
 Top
OSZAR »